Posts filed under 'Medicine'

Cascarets Candy Cathartic

“Just a spoonful of sugar helps the medicine go down…”

Mary Poppins had the right idea, of course. Who wouldn’t rather take their medicine candy-style? As it turns out, the relation between candy and medicine has quite a history. Today, I have for you the story of what I believe to be the first medicine in the U.S. to be marketed nationally as a candy: Cascarets Candy Cathartic.

Cascara, the ingredient suggested by “Cascarets,” is derived from the bitter tasting bark of a species of buckthorn tree native to North America. Cascara had been prescribed by druggists and physicians as a remedy for constipation and related ills as early as 1877. But it was not until 1894 that the Sterling Remedy Company came up with a candy version which would turn out to be a huge blockbuster.

Cascarets were made as brown octagonal tablets reputed to have a “pleasant taste–almost as pleasant as chocolate.” They were put up in rectangular tin boxes of six tablets designed to nestle easily in a vest pocket or small handbag. Cascarets quickly captured the nation. Sterling had offices in Chicago, Minneapolis and New York, facilitating a national distribution of their product. They backed their roll-out with a $500,000 advertising push and incentives to retail druggists. By 1899, Cascarets were selling 5,000,000 boxes per year, and were poised to become the top-selling proprietary medicine in the U.S. (source)

Cascara is a powerful drug with unambiguous effects.  As the science staff at Memorial Sloan-Kettering Hospital explain, “Cascarosides increase intestinal motility and lead to propulsive contractions.” But around 1900, Americans didn’t just associate constipation with abdominal discomfort or gas or indigestion. Constipation for our great-grandparents was the root evil of just about every ailment and malaise you could think of. And for whatever was wrong with you, a laxative (or purgative or cathartic–the terms were used pretty interchangeably) would do the trick.

Cascarets Candy Cathartics were sold as the universal remedy:

When you have Heartburn, Colic, Coated Tongue, Suspected Breath, Acid-rising-in-throat, Gas-belching, or an incipient Cold, take a Cascaret. Remember, all these are not merely Discomforts, but indications of a serious Cause. …A coming Headache can be warded off in short order, by a single Cascaret, and the cause removed. Heartburn, Gas-belching, Acid-risings in the throat, and Colicky feeling are sure signs of bowel trouble from food poisons, and should be dealt with promptly. One Cascaret will stop the coming trouble, and move on the Bowel load, if taken at the first signs. ( 1905 ad)

Cascarets ads included every American as a potential customer: men and women, old and young. Even nursing infants would benefit it mama would take a Cascarets. But the real benefit in the new candy cathartic was the banishment of the old remedy:  castor oil.

Doctors and mothers alike were desperate to find some way of avoiding the nightly struggle to force the nasty liquid down Junior’s screaming throat.  Imagine the relief of American children when Cascarets took the place of the daily dose of castor oil.  Here’s an ad for Cascarets from 1918 that pretty much tells the whole story:

We’ll let Jane and Michael Banks have the last word:

Never be cross or cruel, Never give us Castor oil, or gruel.

And with Cascarets, there would be Castor oil no more.

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  • 1 comment March 15, 2010

    Candy Aspirin, 1952

    Bayer introduced the world’s first flavored, chewable children’s aspirin tablet in 1952. This was a major breakthrough in children’s medicine technology.  One word said it all:  “It tastes like your children’s favorite candy!”

    This new formulation was candy tasting all the way through, unlike earlier “candy” aspirin tablets marketed for children that were bitter medicine surrounded by a sugar coating. So the Bayer tablet could be chewed or dissolve in your mouth, or mixed into a drink or even into food.

    It seemed the answer to a mother’s prayer: “Here’s good news, mother! No more worrisome coaxing, fretting or fussing when your children need aspirin. For the best asprin money can buy now tastes so delicious, they take it with a smile.”

    Of course, if asprin tastes like candy, there is a pretty big problem: kids eating asprin like it is candy. Within three years of the introduction of chewable aspirin, the U.S. FDA had convened a panel of experts to make recommendations to improve the safety of aspirin and reduce childhood deaths due to aspirin poisoning. The panel recommended that aspirin makers develop a “safety closure or container” to prevent children from gobbling down the pills. And so was sown the seed for the child-proof cap.

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  • Sources: Bayer ad, Reading Eagle, June 15, 1952; John Troan, “Accidental Aspirin Deaths Set Up Search for Cure All,” Pittsburgh Press, July 17 1955.

    Add comment March 12, 2010

    Fruits, Candies, and Lydia Pinkham’s Vegetable Compound

    Some time ago, when I was poking around in the dusty archives looking for candy cookbooks with recipes for vegetable candy, I came across a curious item: Fruits and Candies, a recipe booklet from the early 1900s. It was published as a promotion for Lydia E. Pinkham’s Vegetable Compound, a popular women’s  “medicinal tonic” in the early 1900s consisting of various herbs and alcohol (18-20 percent,  stronger than a big California Cabernet but about half as strong as Bacardi white rum).

    This booklet features two sorts of entries: recipes for candies and sweet fruit desserts, and testimonials from ladies whose “female complaints” have been cured by a regular dosing with the Vegetable Compound. So one page offers a recipe for Maple Fondant, followed by a testimonial on the sorrows of childlessness and their alleviation with Lydia Pinkham’s. Another page gives instructions for Buttercups and Molasses Candy, and then a discursus on Painful Monthly Periods and the use of Vegetable Compound to alleviate them.

    What struck me when I first saw this booklet was the complete strangeness of this juxtaposition.  I filed this away under “hmmm.” Surely this odd combination must mean something, but what it meant I couldn’t yet fathom.

    Now I think I have a much better idea. I have been reading about the “pure food” reformers of the late nineteenth and early twentieth century, and particularly the women’s groups that organized against alcohol, drug abuse, and tainted food. These are the grass roots activists whose efforts brought us both Prohibition (something of a catastrophe) and the U.S. Food and Drug Administration (the FDA–not perfect, but one of the better consumer protection success stories of our time).

    One big worry of many reformers in that era was the “patent” medicines: tonics and concoctions made of who-knows-what, peddled in carts and storefronts and by mail, and often containing narcotics (morphine, laudenum, cocaine, alcohol) that led the unsuspecting user who was just looking for a little “pick-me-up” down the merry path of addiction and ruin. The abuse of what the reformers called “habit-forming poisons” was not the intentional and direct narcotic abuse of opium dens or seamy city streets. Customers for the patent formulas were fancy ladies looking for a boost after a night on the town, exhausted mothers just trying to cope, women considered “nervous” or “weak” who saw in the tonics a cure for the mysterious ailments of femininity.

    So one thing the Fruits and Candies booklet tells us is that the “target market” for Lydia Pinkham’s Vegetable Compound was just those middle class women with the leisure and inclination to dabble in home confections.  Somehow, these same women were the ones with numerous and sundry female complaints. And this is the interesting part, to me at least: the connection between middle class leisure, feminine complaint, and confectionery.

    The reformers looked at Lidia Pinkham and the rest and saw addictive potions that would only make things worse. What these women needed was fresh air, good food, and exercise, not 20 percent alcohol “tonics.” One reformer in particular stands out: Ella Kellogg (1853-1920). Ella was the wife of Dr. John Harvey Kellogg (he who brought us corn flakes breakfast cereal), and like her husband she took a strong interest in the importance of good nutrition. Ella believed that it was just those dainty confections that were causing all that nervous female illness. For Ella Kellogg, it was poor nutrition that led to the complaints that caused women to seek relief in the tonics.

    Lydia Pinkham’s Vegetable Compound and candy-making: to Ella Kellogg, the connection would have been quite clear. All that candy eating was making women sick, and sick women were turning to Lydia Pinkham’s Vegetable Compound. To the innocent eye, Fruits and Candies is just advertising packaged to appeal to women by including women’s recipes. To Ella Kellogg and her sisters-in-arms, Fruits and Candies was everything that was wrong with American women.

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  • .
    More: You can browse a full digitized version of Fruits and Candies at Duke University Special Collections. For more on Ella Kellogg’s views of the relation between nutrition and the “patent” medicines so popular in the late nineteenth century, see Lorine Swainston Goodwin, The Pure Food, Drink, and Drug Crusaders, 1879-1914 (1999) (Sorry, this one is a paper book only, no link. Aren’t you glad we still have actual libraries? I am).

    Image source: Vanderbilt Medical Center, via Wikipedia.

    Add comment March 10, 2010

    All About Licorice

    close-up of rolls of liquorices

    First off, Twizzlers aren’t really licorice. In fact, many of the candy we think of as “licorice flavor” is in fact flavored with anise. But real licorice, from the root of the licorice plant, is quite amazing stuff. In a recent post, I described the multitudes of licorice candies that were popular in the early 1900s. And licorice itself played an important part in many American industries in the first half of the twentieth century.

    A little science: glycyrrhizin is the name of the sweet substance in licorice root. This chemical, found in significant levels only in the root of the licorice plant, is fifty times as sweet as sugar. That’s a lot of sweet!

    But the virtues of licorice are not just in the sweetness. Licorice root is a favorite with herbalists today, and boasts a medicinal history going back thousands of years. Licorice root has been used for eons as a health tonic, as a blood purifier, as a means of relief from sore throat and internal inflammations. And it isn’t just good for your insides. Mixed with honey, licorice has been used as a healer of sores and wounds.

    Don’t think it’s just the health-foody types who believe in the healing power of licorice. Modern medical researchers are documenting its effects on the body. Did you know licorice (the real stuff) can raise your blood pressure? Of course, you should consult your doctor if you have questions about the medical effects of licorice. But you can safely consult Candy Professor for information about the history of uses of licorice in confectionery and elsewhere.

    By the 1930s, U.S. industry was importing some 35,000 tons of licorice root per year, for use in a wide variety of industries. Attempts to grow licorice domestically were unsuccessful, so most licorice root was imported from Spain and Italy where it was cultivated commercially.

    The first step in processing the licorice was to shred the roots. Then a process of grinding and sifting and grinding would yield the first product: powdered licorice root, to be used in pharmaceutical prepartions. The coarse remainder would be bathed in a solution, which produced a liquid extract. This second extraction would be reduced to a syrup or paste to form the base needed for candy making, and also for flavoring tobacco.

    But they weren’t finished yet. After candy, cigars, and drugs had taken what they needed, the brewers had a turn. Yes, in the olden days, beer makers would add licorice to their brew to give it a foamy head. And the foaming properties of licorice extract suggested yet another use: fire extinguishers. Licorice extinguishers, which formed an oxygen-free foam, became important in fighting oil fires in the days before chemical extinguishers.

    At last, there was nothing left of the licorice root but stringy fibers. These were not wasted either. The fiber was dried and made into insulating wall and box board. So the box your licorice candy was packaged in might also be made of licorice!

    References: Percy A. Housemna and H. T. Lacey, “The Licorice Root in Industry,” Industrial and Engineering Chemistry, 1929, 21 (10), pp 915–917; “Licorice Industry Reaches Sixtieth Year in America,” New York Times 26 January 1930.

    4 comments February 26, 2010

    The Inventor of Candy Medicine

    Today we honor an unhailed hero of candydom: Dr. Bernard Fantus (1874-1940). He seems an unlikely candidate for the Candy Hall of Fame. He is remembered as the “father of the American Blood Bank,” the first to conceive of collecting and storing a wide variety of blood for surgical and emergency use. But Fantus was a man of many talents and passions, as we shall see.

    In the early 1900s, Dr. Fantus was a Professor of Pharmacology and Therapeutics at the University of Illinois, and also a practicing physician at Cook County Hospital. He was bothered by the difficulties that children had with taking their nasty tasting medicines. Why, Dr. Fantus wondered, should medicine taste like medicine? Let’s make it taste like candy. Good candy. So he set himself to the task.

    Of course, being a medical man, he knew a lot about drugs, but not much about how to make candy. So he signed up for courses with a local candy maker and learned some candy tricks. Then back to his own laboratory, where he experimented with different drugs and formulations. Sulphur taffy was not a success. His next idea was soft, chocolate covered candies with fondant centers to incorporate the medicine. Alas, his cod-liver oil chocolate creams left a little to be desired. There were other problems with fondant based medicines: fondant was tricky to work with, and dried out if stored too long, making it impractical for druggists to keep on hand.

    Finally he hit on the idea of pressed sugar tablets, something akin to today’s American “Smarties.” These were easy to fabricate with a simple hand press and created a base for incorporating some 50 different active drugs. Whether you were bothered by syphilis or malaria, cough or diarrhea, Fantus had a candy tablet to suit. Fantus claimed that his formulations would result in candy tablets that tasted so good that the only problem would be to keep children from overdosing by eating too much at once.

    In the early 1900s, most all prescription drugs were compounded locally by the pharmacist himself. So Fantus didn’t think of actually making any of these candy medications to sell. Instead, Fantus published a booklet titled Candy Medication in 1915 in the hopes that his idea would be taken up by doctors and pharmacists elsewhere. In his preface, he explained the benefits that would come from taking up candy in medical practice:

    It is the author’s hope that this booklet may be instrumental in robbing childhood of one of its terrors, namely, nasty medicine; that it may lessen the difficulties experienced by nurse and mother in giving medicament to the sick child; and help to make the doctor more popular with the little ones.

    Whether other children beyond Fantus’s own practice benefited from his idea is hard to say. But it would be quite some time before a commercial version of “candy medication” became available: children’s chewable aspirin was introduced in 1952.

    References: Bernard Fantus, M.D., Candy Medication (1915); Biography of Dr. Bernard Fantus at My Hero Project

    2 comments February 24, 2010

    Eat More Candy! or not?

    Extreme close-up of mid adult woman eating a chocolate candy bar

    Happy New Year! If your New Year’s Resolutions include a more nutritious diet, you are probably planning to cut down on candy.

    Of course, in different times there have been different ideas about nutrition. Early food science in the late nineteenth century introduced the idea of the “calorie” as a measure of the energy content of food, and recognized three major components of the diet: protein, fat, and carbohydrate.Back in the early 1900s, this food science provided an outstanding rationale for eating more candy.

    For example, one food expert wrote:

    It will be seen that candy has a high energy value–higher than meat, fish and vegetables. From a laboratory point of view, half a pound of chocolate creams, supplemented by a small bag of peanuts, contain all the dietetic elements that are essential for a wholesome and nourishing day’s diet. Three meals can be obtained from the chocolates and peanuts, and the body’s needs be met and the appetite satisfied.

    The craving for sweets also could be framed in scientific terms suggested by ideas of “instinct” and evolutionary utility. A physician offered this explanation:

    Sweets are the necessities of childhood and youth, hence Providence has wisely implanted in the young an insatiable desire for sugar. Without this element largely mingled with its food the healthiest born infant would die in a month. In vain would it nestle on its mother’s bosom, in vain its exposure to the warm sunshine, and in vain the softest blankets and warmest furs to encase its body. For the warmth which sustains human life comes from within, and must be generated by the internal combustion of carbonaceous food as found in all sweets and fats. It is the most inveterate of all prejudices in civilized life that sweets hurt children. On the contarary, they are a prime necessity, and to deprive them of those, if made pure, is downright barbarism.

    Where science led, advertising followed. One candy shop asked:

    Are you eating Candy Enough? The hunger for sweets is natural. The normal man or woman who is not eating a reasonable amount of candy daily is not being properly fed. Recognizing the wholesomeness of the candy DEMAND, we have equipped our store to meet it with a wholesome SUPPLY.

    For us in the twenty-first century, candy is clearly an indulgence, a treat, a little something extra. But the story of candy in the twentieth century was often dominated by a struggle to persuade or prove otherwise, that candy was wholesome and nutritious food. Is it?

    Sources: “Pure Candy is Healthful–Sound the Slogan,” Confectioners Journal Oct 1916, p. 86; “Infancy Dependent Upon Sweets,” Confectioners Journal May 1915, p. 68; Viedts advertisement, Confectioners Journal October 1916, p. 83.
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  • Add comment January 4, 2010

    Igniting Cough Drops

    Violent candies: It’s not about the taste, but about the action. Pop Rocks explode in your mouth. Extreme Sours of all sorts burn the skin off your cheeks. Wintergreen Lifesavers emit sparks when chomped in the dark. Dear candy, don’t just sit there; DO SOMETHING!

    How delightful it must have been for whoever discovered the igniting cough drop, back in 1913. One typically seeks such medicated confection for its soothing, cooling properties. One does not expect pyrotechnics.

    Woman Taking Throat Lozenge

    A popular cough lozenge ingredient in the day was chlorate of potash; mixed up with a little sugar, it promised a tasty and effective treatment for respiratory discomfort. But when you rubbed the lozenge on the igniting strip of a safety-match box, watch out! The lozenge would light up like a match and burn.

    It’s a cough drop. No, it’s a match. No, it’s a cough drop AND a match!

    Confectioners Journal called it “killing two birds with one stone.” One wonders how it could have been as tasty as claimed. Of course, in 1913 those chalky Necco-style wafers were popular, too.

    Source: “Killing Two Birds With One Stone” Confectioners Journal, Jan. 1914 p. 93

    More: Chemistry expert Anne Marie Helmenstine explains Candy Triboluminescence (those sparks from Wintergreen Lifesavers).

    2 comments November 13, 2009

    Candy Band Aids

    Sugar is a somewhat magical substance. In all its many crystalline and syrupy moods it gives us jellies, and taffies, and candy canes, and fudge. These days, we don’t often worry about spoilage, so its easy to forget that sugar is also an excellent preservative. Fruit preserves and candied fruits last a long time; the sugar draws moisture out of the microbes that would make the food spoil.

    Doctor Bandaging a Knee

    None of these uses would suggest that we could use sugar in the arsenal against injury and bloodshed. Yet just such a use was discovered among German surgeons during the early days of the first World War:

    …it is said that many of the wounded have been cured by dressings of ordinary granulated sugar, the compresses being changed every second or third day.

    Actually, it kind of makes sense. Sugar would impede the growth of infectious bacteria, just as it discourages the growth of spoiling bacteria in food. But Confectioners Journal offered a more metaphysical explanation:

    Sugar is always vitalizing and it seems logical that it should purify and heal when thus applied externally.

    And there was a suggestion for a new candy product:

    One of these days our confectioners may be found turning out sugar plasters.

    Candy band aids sounds like a great idea. Imagine how much easier it would be to sooth little Suzy’s scratched knee if you could offer one bandage for the knee, and another to suck on!

    One final thought: Of course, salt would have the same effect. But in addition to the general non-yummyness of salt band aids, it should be pointed out that packing wounds with salt sounds like it would really hurt!

    Source: “Sugar as a Life Saver,” Confectioners Journal April 1917 p 65

    Add comment November 6, 2009

    Laxatives and the end of Trick or Treating

    Halloween is here, and once again we mourn the death of Trick or Treating. It happened exactly fifty years ago, today.

    Thinkstock Single Image Set

    Halloween 1959. Dr. William V. Shyne, a dentist in Fremont, California, was having an off day. Maybe his wife just left him, maybe his pants were too tight, maybe he just didn’t like people. Or rather, maybe he just didn’t like kids.

    Kids came around to his house that night, ringing the bell and calling Trick or Treat! Lots, maybe a couple hundred. In 1959, every kid in America under the age of 10 or so was out on Halloween night, making the rounds. They would go in gangs and groups, the older ones on their own, the littlest ones with older kids or their parents, ringing bells and gathering candy loot and howling and hooting.

    Dr. Shyne answered the door. And he gave out treats, all right. But his treats turned out to be a mean and nasty trick. Police investigators discovered he had “dispensed” 450 candy-coated laxative pills into kids’ outstretched bags. Thirty of those kids became very, very sick.

    Dr. Shyne was charged with “outrage of public decency” and “unlawful dispensing of drugs.” They should have charged him with murder. Because after that, Halloween was never the same.

    Halloween 1960 began the era of “Halloween sadism.” Was it safe to Trick or Treat? What maniac might put a LSD tab, or a poisoned Tootsie Roll, or a razor-spiked apple, in little Suzy’s bag? Stories surfaced of pins, needles, razor blades, but they would fade away under closer examination. Nevertheless, Americans came to believe that kids weren’t safe at Halloween. Parents scrutinized their kiddies’ loot and confiscated anything “wierd.” No cookies, no apples, no unwrapped candies, that was obvious. Some towns set up X-ray stations at hospitals to “check the candy.” The festive and free romping of the streets for Trick or Treat faded into a circuit at the mall, a party at church, a supervised promenade to select neighbors homes.

    But through all of that, even up to today, there has never been a single substantiated instance of an anonymous sadist causing death or life-threatening injury. Not one.

    Dr. Shyne was the first, and only, of his kind.

    RIP.

    PS. I hear, contrary to the boo-hoo-ers, that in fact in many neighborhoods trick or treat is alive and well, with the proper supervision and safeguards. Like the vampires and zombies of Halloween, Trick or Treat rises from the grave!

    2 comments October 30, 2009

    Candy and the Polio Vaccine

    Vaccine on a sugar cube

    Unless you’re over 50, you probably don’t have much experience with polio. It’s a nasty viral infection, which can in bad cases cause paralysis of legs, arms, and in the worst cases, your whole body. Polio gave us the Iron Lung (for paralyzed victims who otherwise would die of asphyxiation) and the March of Dimes, which started out raising money for polio research.

    A vaccine pretty much eliminated polio from the U.S. and most of the developed world in the 1950s. And candy is part of the story.

    In the late 1950s, polio researcher Albert Sabin developed a live virus vaccine to protect against polio. The vaccine had to be taken by mouth. The problem was that it was bitter tasting. Adults might swallow it anyway, but the primary intended beneficiaries of the vaccination programs were children. The obvious solution: put it in candy.

    As early as 1959, scientists and confectioners in the U.S.S.R. had collaborated to produce a candy that could deliver the live virus. We don’t know what the confection tasted like, but it must have tasted pretty good. Over 1.5 million Russian children were successfully immunized by eating the vaccine candy.

    Here in the U.S., Sabin’s live oral vaccine was approved for general use in 1961. Unfortunately, the Russian candy never made it across the ocean; instead, through the 1960s, the oral vaccine was administered to millions of adults and children as a sugar cube. The vaccine was effective; poliomyelitis is virtually unknown in the U.S. today.

    A 1968 article in the New York Times makes the polio vaccine program sound like a party. “Children Frolic and get ‘Candy’ Polio Vaccine” describes a festive event organized by the NYC Health Department at the George Washington Houses in upper Manhattan. With music, toys, balloons and free orange juice, public health officials hoped to draw in pre-schoolers who had not yet been vaccinated against polio. At the event, each child received sugar cube tinted lilac with two drops of the Sabin live oral polio vaccine. Some kids, loving candy, came back for a second piece.

    Too bad every vaccine can’t be candy!

    More: See my research on the role of candy in the 1916 polio epidemic in Articles: The Candy Prophylactic: Danger, Disease, and Children’s Candy around 1916

    Sources: “Children Frolic and get ‘Candy’ Polio Vaccine” New York Times May 22, 1968; “Polio virus Put in Candy” Science News Letter June 27, 1959: 405; “Polio Vaccine Given in Candy, Soviet Says,” New York Times Nov. 26, 1959.

    2 comments October 12, 2009

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    Candy Professor

    The American Candy Century: One hundred years of candy history and culture, fact and fable.

    Samira Kawash, PhD
    Professor Emerita,
    Rutgers University

    Contact:
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    (C) Samira Kawash

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